A vial of a plant-derived COVID-19 vaccine candidate, developed by Medicago, is shown in Quebec City on Monday, July 13, 2020 as part of the company’s Phase 1 clinical trials in this handout photo. Medicago says it has received promising early test results for its plant-derived vaccine for COVID-19. THE CANADIAN PRESS/HO, Medicago

A vial of a plant-derived COVID-19 vaccine candidate, developed by Medicago, is shown in Quebec City on Monday, July 13, 2020 as part of the company’s Phase 1 clinical trials in this handout photo. Medicago says it has received promising early test results for its plant-derived vaccine for COVID-19. THE CANADIAN PRESS/HO, Medicago

Canadian company reports promising early Phase 1 test results of possible COVID-19 vaccine

Quebec City-based company says the side-effects were generally mild to moderate and short in duration

A Canadian biopharmaceutical company says it has received promising early test results for its plant-derived vaccine for COVID-19.

Privately held Medicago says interim results of a Phase 1 clinical trial found that 100 per cent of subjects developed an antibody response after two doses of its COVID-19 vaccine candidate.

“These are very promising results,” said Nathalie Landry, Medicago’s executive vice-president of scientific and medical affairs in a news release.

“We also observed that the antibody levels were higher after vaccination than those observed in convalescent sera from people who recovered from the disease.”

The Quebec City-based company says the side-effects were generally mild to moderate and short in duration.

The Phase 1 clinical trial was a randomized, partially blinded study of 180 healthy people.

Based on the Phase 1 data, Medicago plans to proceed with a Phase 2/3 clinical trial for its COVID-19 vaccine candidate, subject to regulatory approval.

The news comes a day after stock markets worldwide rallied on a report from Pfizer that a potential COVID-19 vaccine it’s developing with German partner BioNTech may be 90 per cent effective, based on early but incomplete test results.

“The positive results of our Phase 1 clinical trial are a step forward in the fight against the COVID-19 pandemic and we are confidently moving forward to our Phase 2/3 trial. We’re pleased that Medicago’s innovative manufacturing technology is helping to diversify the classes of COVID-19 vaccines candidates in development,” said CEO Dr. Bruce Clark.

The federal government has signed a deal with Medicago to secure the rights to buy 76 million doses of its vaccine.

VIDEO: Trudeau says he hopes to see COVID-19 vaccines roll out in Canada in early 2021

Medicago will also receive $173 million in funding from Ottawa for its vaccine research and development and for the construction of its Quebec City manufacturing facility.

Ottawa is also investing $18.2 million in a potential vaccine from British Columbia’s Precision NanoSystems and the National Research Council is to spend $23 million to support other Canadian vaccine initiatives.

Medicago was founded in 1999 and says its team includes over 450 scientific experts and employees in Canada and the United States, with academic affiliations in Europe and South Africa.

The Canadian Press


Like us on Facebook and follow us on Twitter.

Want to support local journalism during the pandemic? Make a donation here.

Coronavirusvaccines

Just Posted

The Nanaimo Timbermen and Victoria Shamrocks compete in Western Lacrosse Association action in Nanaimo during the 2019 season. (News Bulletin file photo)
WLA cancels another senior A lacrosse season due to COVID-19

Western Lacrosse Association, Major Series Lacrosse announce cancellation of Mann Cup

Nanaimo City Hall. (News Bulletin file photo)
City of Nanaimo adopts this year’s tax rates, sends out property tax bills

City says tax increase will amount to $68 for a typical household

Nanaimo RCMP asked the public for help finding a 60-year-old who had been missing since May 9. He has since been found. (Photo submitted)
UPDATE: Nanaimo man located after he had been missing more than a week

Police had expressed concern, noting 60-year-old requires daily medication

A turn-control median at the intersection of Opal and Rock City Roads. (Chris Bush/News Bulletin)
Nanaimo council sticks with Opal Road decision despite residents’ call for reconsideration

Opal Road delegation claims ‘breakdown in the democratic process’

North Cedar Volunteer Fire Department crews at the scene of a single-vehicle crash on Barnes Road near Holden Corso Road in Cedar. (Chris Bush/News Bulletin)
Jeep rolls over on wet afternoon in Nanaimo, occupants OK

Incident happened Monday on Barnes Road in Cedar

North Cedar Volunteer Fire Department crews at the scene of a single-vehicle crash on Barnes Road near Holden Corso Road in Cedar. (Chris Bush/News Bulletin)
Jeep rolls over on wet afternoon in Nanaimo, occupants OK

Incident happened Monday on Barnes Road in Cedar

A prowling coyote proved no match for a stray black cat who chased it out of a Port Moody parking lot Friday, May 14. (Twitter/Screen grab)
VIDEO: Little but fierce: Cat spotted chasing off coyote by Port Moody police

The black cat is seen jumping out from under a parked car and running the wild animal out of a vacant lot

The new wing at the Victoria International Airport opened up on Thursday (File contributed/YYJ)
Pandemic takes ‘hundreds of millions’ out of Victoria Airport, Vancouver Island economy

Airport authority head says passenger volumes down as much as 98 per cent

The top photo is of a real carbine rifle, while the bottom photo is the airsoft rifle seized from a Kelowna man on May 15. (Contributed)
RCMP issue warning: ‘Imitation firearms need to be dealt with responsibly’

A man brandishing his airsoft rifle in public had his weapon seized by Mounties on Saturday

Reigning women’s World Champion Kaetlyn Osmond, who also took bronze at the 2018 Pyeongchang Winter Olympics, will debut two brand new programs for the 2021 Stars On Ice tour, in Victoria May 15. (File photo)
Kurt Browning, Elvis Stojko hit the ice when Stars On Ice returns to Vancouver Island

The star-studded lineup is makes a return after pandemic hiatus

Abbotsford Regional Hospital. (Black Press Media files)
Canada marks 25,000 COVID-19 deaths since the pandemic began

6 in every 10,000 Canadians died of COVID-19 since March 9, 2020

Staff-Sgt. Svend Nielsen, with the 100 Mile House RCMP. (Melissa Smalley - 100 Mile Free Press)
14-year-old boy killed in serious ATV crash near 100 Mile House

Youth was travelling with a group of peers when the incident occurred last Friday

Relief is coming for B.C.’s struggling tourism sector. (NEWS file photo)
B.C. officials set to announce more support for tourism sector hit hard by pandemic

Non-essential travel is restricted between three regional zones in B.C. until at least May 24

This image released by Universal Pictures shows Nathalie Emmanuel, left, and Vin Diesel in a scene from “F9.” (Giles Keyte/Universal Pictures via AP)
The blockbuster movie is making a comeback this summer

Excitement in the industry is growing again for a return to a big-screen normal

Most Read